abstract：PURPOSE:We quantitated herpes simplex virus (HSV) DNA in tear film obtained from 2 patients who developed herpetic epithelial keratitis (HEK) during treatment with latanoprost and a beta-blocker. METHODS:The patient in case 1 is a 77-year-old woman with bilateral open-angle glaucoma who had been treated with latanopro...

journal_title：Cornea

authors： Deai T,Fukuda M,Hibino T,Higaki S,Hayashi K,Shimomura Y

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:To report our experience with 0.05%-2% topical cyclosporine in the treatment of 4 cases of severe, corticosteroid-resistant, vernal keratoconjunctivitis with shield ulcers. METHODS:Four patients with shield ulcers not responding to medical treatment with topical steroids, antihistamines, and mast-cell stabiliz...

journal_title：Cornea

authors： Cetinkaya A,Akova YA,Dursun D,Pelit A

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:The p63 gene has been identified as a marker of epithelial stem cells. Because pterygium may arise through an expansion of the proliferative capacity of the conjunctiva, we sought to document the expression of p63 in normal conjunctiva and pterygium specimens. METHODS:Immunostaining for p63 expression was perf...

journal_title：Cornea

authors： Sakoonwatanyoo P,Tan DT,Smith DR

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To compare the effects of levobunolol hydrochloride and timolol maleate on tear volume, precorneal tear film stability, and corneal epithelial barrier function in normal human eyes. SUBJECTS AND METHODS:The study population consisted of 14 healthy volunteers. To obtain pretreatment baseline values, we determin...

journal_title：Cornea

authors： Ishibashi T,Yokoi N,Kinoshita S

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:To investigate the feasibility of corneal reconstruction utilizing cultured human corneal endothelial cells (HCECs). METHODS:We cultivated HCECs using culture dishes pre-coated with bovine corneal endothelial extracellular matrix. The effect of donor age on HCECs was investigated. We reconstructed corneas usin...

journal_title：Cornea

authors： Amano S

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To describe the Oxford Scheme for grading ocular surface staining in dry eye and to discuss optimization of stain detection using various dyes and filters. Also, to propose a sequence of testing for dry eye diagnosis. METHODS:The grading of corneal and conjunctival staining is described, using the Oxford Schem...

journal_title：Cornea

authors： Bron AJ,Evans VE,Smith JA

更新日期：2003-10-01 00:00:00

abstract：PURPOSE:To evaluate the accuracy and precision of corneal flap thickness following laser in situ keratomileusis (LASIK) performed using the 140-, 160-, and 180-microm heads for the Amadeus microkeratome (AMO, Irvine, CA). SETTING:The study took place at the Cullen Eye Institute, Baylor College of Medicine, Houston. M...

journal_title：Cornea

authors： Jackson DW,Wang L,Koch DD

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:To evaluate long-term follow-up of high-risk corneal transplants allocated after matching for broad HLA-A and HLA-B antigens and to establish whether matching for HLA-A and -B antigen "splits" would result in a reduced risk of immunologic graft failure. METHODS:A total of 303 high risk corneal transplants was ...

journal_title：Cornea

authors： Bartels MC,Doxiadis II,Colen TP,Beekhuis WH

更新日期：2003-08-01 00:00:00

abstract：PURPOSE:Corneal inflammation in overnight contact lens (CL) wear is not fully understood. We designed a masked study to examine the impact of overnight CL wear on clinical variables in subjects who had previously experienced corneal inflammatory disease. METHODS:Forty-four subjects were entered into the study: Nine su...

journal_title：Cornea

authors： Stapleton F,Ramachandran L,Sweeney DF,Rao G,Holden BA

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To present four cases of localized corneal amyloidosis secondary to trichiasis and to discuss its pathogenesis. METHODS:Medical and pathologic records of four patients with corneal amyloidosis secondary to trichiasis were reviewed retrospectively. Two patients underwent trichiasis surgery and then lamellar ker...

journal_title：Cornea

authors： Lin PY,Kao SC,Hsueh KF,Chen WY,Lee SM,Lee FL,Shiuh WM

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:To review the clinical course, treatment, and visual outcomes of keratitis with endophthalmitis caused by the filamentary fungus Fusarium. METHOD:One hundred fifty-nine cases of Fusarium keratitis at Bascom Palmer Eye Institute between January 1, 1987 and August 21, 2000 were reviewed. Ten patients with cultur...

journal_title：Cornea

authors： Dursun D,Fernandez V,Miller D,Alfonso EC

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:To provide insight into the mechanism by which epidermal growth factor (EGF) stimulates corneal epithelial migration, we investigated the possible interaction between EGF and cyclic AMP (cAMP) signaling pathways during epithelial migration with an organ culture system for the rabbit cornea. METHODS:Rabbit corn...

journal_title：Cornea

authors： Nakamura M,Nishida T

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:The study aimed to determine whether detectable concentrations of colchicine are present in the tear fluid of treated patients with familial Mediterranean fever (FMF) and thus demonstrate a possible route by which colchicine reaches the corneal surface. METHODS:Tear fluid samples (50-100 microL) were collected...

journal_title：Cornea

authors： Leibovitch I,Alster Y,Scherrmann JM,Azmon B,Barequet IS,Livneh A,O'Brien TP,Lazar M,Loewenstein A

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To determine whether there is an association between keratoconus and personality attributes including obsessionality traits. METHODS:We reviewed all charts in the regional contact lens clinic, identifying patients who had attended from January 1997 to January 2000 and had a diagnosis of either keratoconus or m...

journal_title：Cornea

authors： Cooke CA,Cooper C,Dowds E,Frazer DG,Jackson AJ

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:The normal cornea is devoid of blood and lymphatic vessels but can become vascularized secondary to a variety of corneal diseases and surgical manipulations. Whereas corneal (hem)angiogenesis, i.e., the outgrowth of new blood vessels from preexisting limbal vessels, is obvious both clinically and histologically...

journal_title：Cornea

authors： Cursiefen C,Chen L,Dana MR,Streilein JW

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:To compare the effect of a 3- and 5-minute intraoperative application of topical mitomycin C 0.02% on the recurrence of pterygium. METHODS:A comparative, prospective clinical design was used. The study population consisted of 134 consecutive patients with unilateral primary advanced pterygium (growth of 3 mm o...

journal_title：Cornea

authors： Avisar R,Gaton DD,Loya N,Appel I,Weinberger D

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To determine the stability of the laser in situ keratomileusis (LASIK) flap in a rabbit model when subjected to vertical acceleration at nine times the force of gravity (+9 Gz) in an aircraft cockpit ejection simulator. METHODS:Thirty-six eyes from 25 New Zealand white rabbits underwent LASIK flap creation wit...

journal_title：Cornea

authors： Goodman RL,Johnson DA,Dillon H,Edelhauser HF,Waller SG

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To report a case of epithelial ingrowth (downgrowth) occurring in a phakic corneal transplant patient after traumatic wound dehiscence with iris prolapse that was successfully eradicated with early surgical intervention. METHODS:Interventional case report of a 70-year-old monocular, phakic patient who develope...

journal_title：Cornea

authors： Nagra PK,Raber IM

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:To determine whether canalicular occlusion with collagen and silicone plugs reduces the severity of symptoms in patients with conjunctivitis secondary to dry eye. METHODS:This was a prospective, randomized, double-masked study conducted at a single center in Mexico, in which 61 patients with dry eye/conjunctiv...

journal_title：Cornea

authors： Nava-Castaneda A,Tovilla-Canales JL,Rodriguez L,Tovilla Y Pomar JL,Jones CE

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To report a case of insect corneal foreign body with in vivo confocal microscopy performed. METHODS:Clinical presentation, clinical pictures, and treatment are discussed. Confocal microscopy of the injured cornea was performed in areas showing foreign bodies with and without infiltrations seen under the slit-l...

journal_title：Cornea

authors： Wong BW,Lai JS,Law RW,Lam DS

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To report a case of direct contact xylene-related vacuolar keratopathy. METHODS:Interventional case report and review of the literature. RESULTS:Xylene keratopathy is a distinct clinical entity characterized by significantly decreased visual acuity, increased corneal thickness, and the presence of corneal epi...

journal_title：Cornea

authors： Trujillo F,Dang D,Starck T

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:To examine the immediate effect of ocular rubbing on corneal topography. METHODS:Corneal topography and analysis were performed before, immediately after, and 5 minutes after eyelid rubbing in 29 volunteers without ocular disease. RESULTS:The surface regularity index increased from a baseline of 0.24 to 0.91 ...

journal_title：Cornea

authors： Mansour AM,Haddad RS

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:To assess the reproducibility of relatives' replies to questions asked at the time of corneal donation and again 2 months later concerning infectious disease risk factors and to identify characteristics associated with inconsistent responses. METHODS:A reinterview study involving individuals who answered quest...

journal_title：Cornea

authors： Scardino MK,Hwang SJ,Hanna CL,Danneffel-Mandelkorn MB,Wilhelmus KR

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:To review the development of artificial corneas (prostheses and tissue equivalents) for transplantation, and to provide recent updates on our tissue-engineered replacement corneas. METHODS:Modified natural polymers and synthetic polymers were screened for their potential to replace damaged portions of the huma...

journal_title：Cornea

authors： Griffith M,Hakim M,Shimmura S,Watsky MA,Li F,Carlsson D,Doillon CJ,Nakamura M,Suuronen E,Shinozaki N,Nakata K,Sheardown H

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To report the use of intracameral amphotericin B in the management of deep keratomycosis. METHODS:Four patients with deep keratomycosis unresponsive to conventional medical treatment underwent repeated intracameral injections of 5 microg amphotericin B in 0.1 mL 5% dextrose through a paracentesis. Three to 13 ...

journal_title：Cornea

authors： Kuriakose T,Kothari M,Paul P,Jacob P,Thomas R

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To describe whether deep lamellar keratectomy with a conjunctival flap is effective for the treatment of Acanthamoeba keratitis. METHODS:Two patients (three eyes) had at least a 4-week history of painful keratitis misdiagnosed as herpetic keratitis and bacterial keratitis. Both patients were started on multipl...

journal_title：Cornea

authors： Cremona G,Carrasco MA,Tytiun A,Cosentino MJ

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To examine the incidence of sporadic diffuse lamellar keratitis (DLK) in a large series of LASIK eyes and to suggest the hypothesis that the etiology of sporadic DLK differs from that of epidemic DLK. METHODS:The incidence and severity of DLK was noted in 1352 consecutive eyes that had primary LASIK for myopia...

journal_title：Cornea

authors： Wilson SE,Ambrósio R Jr

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To report a case of traumatic flap partial dislocation and subsequent diffuse lamellar inflammation 14 months after laser in situ keratomileusis (LASIK) retreatment. METHODS:Case report of a late flap dislocation that occurred during routine recreational activity (struck with a finger in the right eye while pl...

journal_title：Cornea

authors： Aldave AJ,Hollander DA,Abbott RL

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To assess the morphologic differences of three types of lattice corneal dystrophies (LCDs) from histologic, immunohistochemical, and ultrastructural studies. METHODS:Corneas from three patients, one LCD1, one His626Arg-LCD, and one LCD3A were processed for Congo red, betaig-h3(541-564) antibodies immunostainin...

journal_title：Cornea

authors： Schmitt-Bernard CF,Schneider C,Argilés A

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:We report our experience in treating two cases of Scedosporium apiospermum keratitis and provide a review of basic scientific and clinical data regarding the treatment of this visually devastating disease. METHOD:We present a case report and literature review. RESULTS:A 35-year-old woman and a 73-year-old man...

journal_title：Cornea

authors： Wu Z,Ying H,Yiu S,Irvine J,Smith R

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:We aimed to minimize the effect of ocular microfluctuations during videokeratoscopy to improve the qualitative and quantitative analysis of corneal topography. METHODS:A technique was developed to measure the tilt, displacement, and cyclotorsion in multiple videokeratographs from the same cornea. This informat...

journal_title：Cornea

authors： Buehren T,Lee BJ,Collins MJ,Iskander DR

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To report the histologic findings in three explanted osteo-odontokeratoprosthesis (OOKP) laminae. METHODS:The osteodental lamina of patient 1 with linear IgA bullous dermatosis had to be explanted 15 months after OOKP surgery because of permanent leakage after the resorption of the inferior half of the bone/de...

journal_title：Cornea

authors： Stoiber J,Csáky D,Schedle A,Ruckhofer J,Grabner G

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:To report the incidence of complications and the refractive results in patients with diabetes mellitus treated with laser-assisted in situ keratomileusis (LASIK). METHODS:A retrospective review of the charts, focusing on 6-month postoperative data, was performed on 30 eyes from patients with diabetes and 150 a...

journal_title：Cornea

authors： Fraunfelder FW,Rich LF

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:To report two patients with glaucoma who exhibited severe damage to the corneal endothelium after a trabeculectomy with mitomycin C (MMC). METHODS:This study includes clinical histories and specular microscopic pictures of the cases. RESULTS:Both patients were middle-aged women, underwent trabeculectomy with ...

journal_title：Cornea

authors： Fukuchi T,Hayakawa Y,Hara H,Abe H

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:Subepithelial amyloidosis of the cornea, or gelatinous drop-like corneal dystrophy (GDD), is a severe form of corneal stromal amyloidosis predominantly found in the Japanese population. GDD causes severe visual disturbances with irritating symptoms, and keratoplasty is inevitably complicated by early recurrence...

journal_title：Cornea

authors： Shimazaki J,Shimmura S,Tsubota K

更新日期：2002-03-01 00:00:00

abstract：:We present two cases of posterior amorphous corneal dystrophy in members of the same family. We correlated the clinical findings with refraction, topography, and ultrasound biomicroscopy (UBM). This is the first report of UBM findings in amorphous corneal dystrophy and we describe the depth of stromal opacification me...

journal_title：Cornea

authors： Castelo Branco B,Chalita MR,Casanova FH,Castelo Branco AB,Allemann N,de Freitas D

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of intraoperative mitomycin-C in excision of ocular surface neoplasia for prevention of recurrence. METHODS:Seven patients (eight eyes), three men and four women, aged 56 to 87 years (mean, 73.8 years), with lesions suspicious for corneal or conjunctival neoplasia, were operated on bet...

journal_title：Cornea

authors： Siganos CS,Kozobolis VP,Christodoulakis EV

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:To examine the applicability of culture supernatant of human amniotic cells on basic fibroblast growth factor (bFGF)-induced corneal neovascularization. METHODS:Human amniotic epithelial and mesenchymal cells (AC) were obtained from human amniotic membranes by digesting with collagenase and maintained in serum...

journal_title：Cornea

authors： Kobayashi N,Kabuyama Y,Sasaki S,Kato K,Homma Y

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:Videokeratoscopes provide a wealth of information about the topography of the ocular surface. Although there have been numerous studies of the accuracy and precision of videokeratoscopes with inanimate test objects, little information exists on their precision (repeatability) for real eyes. METHODS:To investig...

journal_title：Cornea

authors： Buehren T,Collins MJ,Iskander DR,Davis B,Lingelbach B

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To determine the effectiveness of prophylactic fluoroquinolone treatment against staphylococci in a rabbit keratitis model. METHODS:Prophylactic ciprofloxacin or ofloxacin was applied as one topical drop 15 minutes before infection or as one drop at three time points (19, 17, and 15 minutes) before infection. ...

journal_title：Cornea

authors： Dajcs JJ,Moreau JM,Thibodeaux BA,Traidej M,Austin MS,Marquart ME,Stroman DW,O'Callaghan RJ

更新日期：2001-11-01 00:00:00